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Cyplasin Biomedical Ltd Announces Japanese Patent for its Antitumor Protein Edmonton, Alberta, May 20, 2008 CYPL: OTCBB, Frankfurt Exchange WKN:XYIA Cyplasin Biomedical Ltd (CBL)., today announced that its Japanese patent application NrHei 9-516992 has been granted. The claims cover the characterization of a cytotoxic protein from the mucus of the sea hare Aplysia punctata and its use to treat cancer. “It is gratifying to receive the approval of our patent application since it was obtained after many years of careful in-depth-analysis by the Japanese Patent Office. It describes our intellectual property for the cytotoxic cyplasin to be used as an anticancer substance, especially valuable in one of the most important economies worldwide. Together with corresponding US and European patents, Cyplasin Biomedical Ltd relies now on a solid intellectual property portefeuille allowing it to proceed successfully in the rapid development of cyplasin,” said Professor Christian Petzelt, Chief Scientific Officer of Cyplasin Biomedical Ltd. About Melanoma Around 160,000 new cases of new melanoma cases are diagnosed worldwide each year. Melanoma is more frequently found in caucasian males and is more common in caucasian populations living in sunny climates than in other groups. Market statistics for skin cancer and melanoma show that melanoma currently affects more then 2.4 million people worldwide with 62,000 new cases being reported in the USA every year. Australia has the highest rate of melanoma in the world among males and has the second highest rate in the world among females (Australia’s Health 2004, AIHW). According to a WHO Report the world wide incidence has doubled over the past 20 years with about 48,000 melanoma related deaths occurring worldwide per annum. About Cyplasin-SC™ Cyplasin-SC™ has demonstrated a selective ability to rapidly kill certain types of cancer cells while leaving normal non-cancerous cells untouched. Cyplasin-SC is a protein originally discovered and isolated by Professor Petzelt from a marine organism, the sea hare (Aplysia punctata). The protein can now be manufactured as a recombinant protein which allows the company to develop the protein as an anti-cancer therapeutic product. United States and European patents have been issued to the Company covering the Cyplasin-SC protein. About Cyplasin Biomedical Ltd. (CBL) Founded in 2007 and headquartered in Edmonton, Canada, CBL is dedicated to bring new anticancer therapeutics to the marketplace. The Company’s current goal is to develop and commercialize the anticancer properties of Cyplasin-SC™ against skin cancer and melanoma. CBL is publicly traded (CYPL: OTCBB) Forward-Looking Statements This Press release includes and is based, inter alia, on forward-looking information and statements that are subject to risks and uncertainties that could cause actual results to differ. Such forward-looking information and statements are based without limitation, as statements regarding future drug development activities, anticipated products, or anticipated future revenues, benefits or advantages, and the future plans and objectives of the Company, that involve inherent risks and uncertainties and are subject to factors, many of which are beyond the Company's control, such as market acceptance of new products and services, changes in governmental regulations, interest rates, fluctuations in currency exchange rates and such other factors as may be discussed from time to time that may cause actual results or performance to differ materially from those currently anticipated in such statements. These expectations, estimates and projections are generally identifiable by statements containing words such as "expects", "believes", "estimates" or similar expressions. Although Cyplasin Biomedical Ltd., believes that its expectations and the information in this Press release were based upon reasonable assumptions at the time when they were made, it can give no assurance that those expectations will be achieved or that the actual results will be as set out in this Press release. Cyplasin Biomedical Ltd., makes no representation or warranty, expressed or implied, as to the accuracy, reliability or completeness of the information in the Press release, and neither Cyplasin Biomedical nor any of their directors, officers or employees will have any liability to you or any other persons resulting from your use of the information in the Press release. The OTCBB Exchange has not reviewed and does not accept responsibility for the adequacy or accuracy of this news release. Contact:
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